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A selective growth hormone secretagogue pentapeptide composed of 5 amino acids. Demonstrates high selectivity for the ghrelin/GHS receptor with minimal effect on cortisol, prolactin, or ACTH in research models.
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In-depth findings from peer-reviewed preclinical and clinical studies
Ipamorelin is a selective growth hormone secretagogue pentapeptide that binds the ghrelin/GHS-R1a receptor with high specificity, stimulating GH release without affecting cortisol, ACTH, or prolactin levels.
Ipamorelin selectively stimulated growth hormone release via the GHS-R1a receptor without significantly elevating ACTH, cortisol, FSH, LH, prolactin, or TSH — demonstrating high endocrine specificity among GH secretagogues.
European Journal of Endocrinology (1998)In controlled experimental settings, Ipamorelin demonstrated dose-dependent GH release with corresponding elevations in IGF-1. Human pharmacokinetic studies showed a terminal half-life of approximately 2 hours with peak GH release at ~40 minutes post-administration.
Journal of Clinical Pharmacology (1999)Ipamorelin dose-dependently increased longitudinal bone growth rate in animal models and counteracted the decrease in bone formation induced by glucocorticoid (dexamethasone) treatment.
Growth Hormone & IGF Research (2001)In glucocorticoid-treated rats, Ipamorelin treatment preserved total body bone mineral content and promoted bone formation markers, suggesting protective effects against corticosteroid-induced bone loss.
Endocrinology (2000)All findings above are sourced from peer-reviewed journals for educational reference. This product is for research purposes only — not for human consumption. Preclinical results may not translate to human outcomes.
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All products are for research and laboratory purposes only. Not intended for human or animal consumption. Only qualified professionals should handle these products.