SS-31 (Elamipretide)
10mgVolume Pricing
Per unit — bulk discounts applied automaticallyWholesale pricing available for approved accounts
About SS-31 (Elamipretide)
A mitochondrial-targeted peptide that binds to cardiolipin, a lipid found almost exclusively in the inner mitochondrial membrane. SS-31 is studied for its ability to restore mitochondrial bioenergetics, reduce reactive oxygen species (ROS) production, and improve cellular function in models of oxidative stress, ischemia-reperfusion injury, and aging-related diseases.
Frequently Asked Questions
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Published Study Findings on SS-31 (Elamipretide)
Detailed Research & Citations
In-depth findings from peer-reviewed preclinical and clinical studies
SS-31 (Elamipretide) is a mitochondria-targeted peptide that selectively binds to cardiolipin in the inner mitochondrial membrane, restoring mitochondrial bioenergetics and reducing oxidative stress in research models.
Cardiolipin Binding and Stabilization
SS-31 selectively binds to cardiolipin, a unique phospholipid in the inner mitochondrial membrane, stabilizing its structure and function. This interaction restores electron transport chain efficiency and enhances ATP synthesis.
Journal of Biological Chemistry (2014)Reduction of Mitochondrial ROS
By optimizing the electron transport chain, SS-31 significantly reduces the production of reactive oxygen species (ROS) at their source, providing targeted protection against oxidative stress-induced cellular damage.
Journal of the American Society of Nephrology (2011)Protection Against Ischemia-Reperfusion Injury
In preclinical models of myocardial infarction, SS-31 administration reduced infarct size, preserved mitochondrial structure, and improved functional recovery following ischemia-reperfusion injury.
British Journal of Pharmacology (2014)View All 3 Sources
- Cardiolipin provides structural and functional safeguards for the mitochondrial electron transport chain
- Mitochondria-targeted peptide accelerates ATP recovery and reduces ischemic kidney injury
- First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics
All findings above are sourced from peer-reviewed journals for educational reference. This product is for research purposes only — not for human consumption. Preclinical results may not translate to human outcomes.
Chemical Identity
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